Reid wrote sexually explicit versions of hit songs for fun but only performed them for his friends at parties or in the studio. In 1971, he along with a band of studio musicians recorded a whole album of dirty songs under the name Blowfly. The album, The Weird World of Blowfly, features Reid dressed as a low-rent supervillain on its cover. He created this alter ego to protect his career as a songwriter, and continued to perform in bizarre costumes as his Blowfly character and continued to record sexually explicit albums throughout the 1970s/80s. The albums were widely popular as "party records". The explicit version of his song "Rapp Dirty" (a.k.a. "Blowfly's Rapp [sic]") helped the album Blowfly's Party reach #26 on Billboard magazine's Black Albums chart and #82 on the Billboard Top 200 in 1980.
Blowfly's profane style earned Reid legal trouble. He was sued by songwriter Stanley Adams, who was ASCAP president at the time, for spoofing "What a Diff'rence a Day Makes" as "What a Difference a Lay Makes". Reid's own compositions have been sampled by dozens of hip hop, R&B, and electronic artists (such as Beyonce, Wu Tang Clan, DJ Quik, DMX, Method Man & Redman, Main Source, DJ Shadow, Eazy-E, RJD2, Jurassic 5, Big Daddy Kane, Mary J. Blige, Brand Nubian, and the Avalanches) but Reid has received almost no money from sampling due to signing away most of his royalties.